A Study of DS-3939a in Participants With Solid Tumors

The primary purpose of the study is to evaluate the safety, tolerability, and efficacy of DS-3939a in combination with other anticancer agents or as a monotherapy in participants with solid tumors.

Trial Details

NCT ID
NCT07739966
Phase
PHASE1 / PHASE2
Sponsor
Daiichi Sankyo
Status
RECRUITING
Cancer Type
Non-Small Cell (NSCLC) Lung Cancer
Interventions
  • DS-3939a
  • Pembrolizumab
  • Carboplatin
  • Pemetrexed
  • DS-1103a
Locations (sample)
  • Fayetteville, Arkansas, United States|36.06258,-94.15743
  • Los Angeles, California, United States|34.05223,-118.24368
  • Tampa, Florida, United States|27.94752,-82.45843
  • Portland, Oregon, United States|45.52345,-122.67621
  • Providence, Rhode Island, United States|41.82399,-71.41283

Key Eligibility Criteria

  • Sign and date the Main Trial informed consent form (ICF), prior to the start of any trial-specific procedures.
  • Adults greater than or equal to (≥)18 years of age at the time the Main Trial ICF is signed (follow local regulatory requirements if the legal age …
  • Histologically documented Stage IIIB, IIIC disease who is not candidate for surgical resection or definitive chemoradiation, or Stage IV NSQ NSCLC.
  • Has a left ventricular ejection fraction (LVEF) ≥50 percent (%) by either an echocardiogram (ECHO) or multigated acquisition scan (MUGA) within 28 …

For full eligibility, visit ClinicalTrials.gov.

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