Adaptive Dosing of Immune Checkpoint Inhibitors for Hepatocellular Carcinoma

The goal of this clinical trial is to learn if immunotherapy including nivolumab plus ipilimumab is effective and safe in treating hepatocellular carcinoma.

Trial Details

NCT ID
NCT07689175
Phase
PHASE2
Sponsor
University of Texas Southwestern Medical Center
Status
RECRUITING
Cancer Type
Liver Cancer
Interventions
  • Nivolumab
  • Ipilimumab (3 mg/kg)
Locations (sample)
  • Dallas, Texas, United States|32.78306,-96.80667

Key Eligibility Criteria

  • Patient must have a diagnosis confirmed by histology or clinically by the American Association for the Study of Liver Diseases (AASLD) criteria in …
  • Patients may not have received any prior anti-PD-1/L1 or anti-CTLA-4 therapies for the treatment of advanced HCC.
  • Patients with locally advanced or metastatic disease must have disease deemed not amenable to surgical and/or locoregional therapies or patients wh…
  • Child-Pugh Score B7-8

For full eligibility, visit ClinicalTrials.gov.

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