A Study To Assess the Safety, Tolerability, and Efficacy of Imzokitug in Combination With Pumitamig and Platinum-Doublet Chemotherapy (PDCT) Versus Pumitamig and PDCT as First-line Treatment for Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

The purpose of this study is to assess the safety, tolerability, and efficacy of Imzokitug in combination with Pumitamig and Platinum-Doublet Chemotherapy (PDCT) versus Pumitamig and PDCT as first-line treatment for participants with Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Trial Details

NCT ID
NCT07680764
Phase
PHASE2
Sponsor
Bristol-Myers Squibb
Status
RECRUITING
Cancer Type
Lung Cancer
Interventions
  • Pumitamig
  • Imzokitug
  • Pemetrexed
  • Cisplatin
  • Carboplatin
  • Paclitaxel
Locations (sample)
  • Washington D.C., District of Columbia, United States|38.89511,-77.03637
  • Athens, Georgia, United States|33.96095,-83.37794
  • Lexington, Kentucky, United States|37.98869,-84.47772
  • Baltimore, Maryland, United States|39.29038,-76.61219
  • Hattiesburg, Mississippi, United States|31.32712,-89.29034

Key Eligibility Criteria

  • Participants must have histologically confirmed diagnosis of stage IV non-small cell lung cancer (NSCLC) (squamous or non-squamous) or recurrent un…
  • Participants must have no prior systemic anti-cancer therapy given as primary therapy for advanced or metastatic disease.
  • Tumor tissue (fresh or archival) obtained within 5 months of enrollment (signing of informed consent) for each participant must be submitted by the…
  • Participants must have an Eastern Cooperative Oncology Group Performance Status of 0 or 1.

For full eligibility, visit ClinicalTrials.gov.

Check If You May Be Eligible

Trialify translates complex eligibility criteria into plain yes-or-no questions to help you understand if this trial might be right for you.

Find Lung Cancer Trials on Trialify →