Adaptive Daily MR-Guided Adjuvant Pelvic Therapy-Endometrial Cancer

To evaluate the safety, tolerability, and preliminary efficacy of moderately hypofractionated (15-fraction) MR-guided adaptive pelvic IMRT in patients with endometrial cancer.

Trial Details

NCT ID
NCT07643012
Phase
NA
Sponsor
Rutgers, The State University of New Jersey
Status
RECRUITING
Cancer Type
Uterine Cancer
Interventions
  • MR-guided adaptive pelvic intensity-modulated radiation therapy (IMRT)
Locations (sample)
  • New Brunswick, New Jersey, United States|40.48622,-74.45182

Key Eligibility Criteria

  • Histologically confirmed endometrial carcinoma (endometrioid, serous, clear cell, carcinosarcoma, or dedifferentiated histology).
  • Indication for adjuvant pelvic radiotherapy (± vaginal brachytherapy) for HIR defined by the ASTRO guidelines and GOG-99(7, 9) :
  • High-grade histology (grade 2-3)
  • Depth of myometrial invasion

For full eligibility, visit ClinicalTrials.gov.

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