Autologous Fat Grafting for Total Breast Reconstruction in Irradiated Breast Cancer Patients

The goal of this clinical trial is to learn whether autologous fat transfer (AFT) is as effective and safe as Deep Inferior Epigastric Perforator (DIEP) flap breast reconstruction in irradiated breast cancer patients following mastectomy. It will also evaluate patient satisfaction, quality of life, complication rates, and cost-effectiveness of both reconstruction techniques. The main questions it aims to answer are: Does AFT result in non-inferior patient satisfaction with the reconstructed breast compared to DIEP flap reconstruction 12 months after the final operation? Does AFT result in few

Trial Details

NCT ID
NCT07641985
Phase
NA
Sponsor
Maastricht University Medical Center
Status
RECRUITING
Cancer Type
Breast Cancer
Interventions
  • Autologous fat transfer
  • Deep inferior epigastric perforator flap
Locations (sample)
  • Maastricht, Limburg, Netherlands|50.84833,5.68889

Key Eligibility Criteria

  • Female, aged \>18 years.
  • BMI between \> 22 and \<35 kg/m2
  • History of breast cancer treated with mastectomy (minimally 3 months after mastec-tomy) and post mastectomy chest wall radiotherapy (completed ≥6 m…
  • May include contralateral/bilateral prophylactic mastectomy if at least one side had cancer and radiation.

For full eligibility, visit ClinicalTrials.gov.

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