An Open-label, Single-arm, Multicenter Phase II Clinical Study of Azacitidine, Chidamide Combined With PD-1 Monoclonal Antibody in the Treatment of Refractory/Relapsed Peripheral T-cell Lymphoma.

An Open-Label, Single-Arm, Multicenter Phase II Clinical Study to Evaluate the Efficacy of Azacitidine, Chidamide, and PD-1 Monoclonal Antibody in the Treatment of Refractory/Relapsed Peripheral T-Cell Lymphoma.

Trial Details

NCT ID
NCT07598578
Phase
EARLY_PHASE1
Sponsor
Second Affiliated Hospital of Soochow University
Status
RECRUITING
Cancer Type
Lymphoma
Interventions
  • Azacitidine (AZA)
Locations (sample)
  • Suzhou, China|31.30408,120.59538

Key Eligibility Criteria

  • Age ≥18 years and ≤75 years, male or female.
  • Histologically confirmed peripheral T-cell lymphoma (PTCL) by the investigating center, including: peripheral T-cell lymphoma, not otherwise specif…
  • Relapsed or refractory disease after at least one prior line of systemic therapy. Relapse is defined as disease recurrence after complete response …
  • Patients considered ineligible for autologous hematopoietic stem cell transplantation by the investigator, or those who refuse such treatment.

For full eligibility, visit ClinicalTrials.gov.

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