Comparing Two Different Boost Approaches in Radiation Therapy for People With Prostate Cancer

In this study the investigators will find out whether the use of a new type of boost approach called irreversible electroporation (IRE) is as effective as the standard boost approach of radiation therapy for participants with intermediate-risk prostate cancer receiving standard stereotactic body radiotherapy (SBRT).

Trial Details

NCT ID
NCT07548164
Phase
PHASE3
Sponsor
Memorial Sloan Kettering Cancer Center
Status
RECRUITING
Cancer Type
Prostate Cancer
Interventions
  • NanoKnife System
  • Stereotactic Body Radiation Therapy
Locations (sample)
  • Basking Ridge, New Jersey, United States|40.70621,-74.54932
  • Middletown, New Jersey, United States|40.39428,-74.11709
  • Montvale, New Jersey, United States|41.04676,-74.02292
  • Commack, New York, United States|40.84288,-73.29289
  • Harrison, New York, United States|40.96899,-73.71263

Key Eligibility Criteria

  • Biopsy proven grade group 2 or 3 (GS 3+4 or GS 4+3) cancer with all pattern 4 found only in the MRI target; systematic biopsy pattern 4 that is con…
  • Gland size ≤ 80 cc
  • Prostate MRI \< rT3b disease
  • IPSS \< 20

For full eligibility, visit ClinicalTrials.gov.

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