Phase II Clinical Study of Probiotic LR607 in Patients With Non-Small Cell Lung Cancer

The goal of this clinical trial is to understand whether Lactobacillus rhamnosus LR607 can enhance neoadjuvant chemoimmunotherapy for adult patients with non-small cell lung cancer. It will also evaluate the safety of LR607. The main questions it aims to answer include: Can LR607 improve the major pathological response of neoadjuvant chemoimmunotherapy? What is the relationship between LR607 combined with neoadjuvant chemoimmunotherapy and treatment-related adverse reactions? What changes occur in the gut microbiota composition at the species level and gut metabolites of subjects after LR607

Trial Details

NCT ID
NCT07534033
Phase
PHASE2
Sponsor
Zhujiang Hospital
Status
RECRUITING
Cancer Type
Lung Cancer
Interventions
  • Probiotics combined with neoadjuvant chemoimmunotherapy
Locations (sample)
  • Guangzhou, China|23.11667,113.25

Key Eligibility Criteria

  • Histologically confirmed newly diagnosed patients
  • ECOG performance status 0-1
  • Age ≥18 years
  • Measurable lesions (RECIST v1.1)

For full eligibility, visit ClinicalTrials.gov.

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