Radiation, Oral Vancomycin, and CAR-T for B-Cell Lymphomas

This clinical trial assesses whether it is feasible to use radiation therapy with vancomycin prior to CAR T-cell therapy for patients with large B-cell lymphomas

Trial Details

NCT ID
NCT07478848
Phase
PHASE1
Sponsor
Abramson Cancer Center at Penn Medicine
Status
RECRUITING
Cancer Type
Lymphoma
Interventions
  • Vancomycin 125mg
  • Radiation Therapy
  • CAR-T
Locations (sample)
  • Philadelphia, Pennsylvania, United States|39.95238,-75.16362

Key Eligibility Criteria

  • Male or female subject aged ≥ 18 years.
  • Pathologically confirmed B-cell lymphoma patients intended for standard of care CAR-T
  • ECOG Performance Status ≤ 2.
  • Subjects must be clinically eligible to receive standard of care anti-CD19 CAR-T

For full eligibility, visit ClinicalTrials.gov.

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