Creatine Supplementation and Resistance Training to Improve Sarcopenia Parameters in Patients With Prostate Cancer After Androgen Deprivation Therapy

This randomized, double-blind, placebo-controlled clinical trial will investigate the effects of creatine supplementation combined with a 12-week supervised resistance training program on muscle mass, muscle strength, physical performance (e.g., parameters of sarcopenia), and muscle density in men with prostate cancer undergoing androgen deprivation therapy (ADT). ADT often causes loss of lean mass, reduced muscle strength, functional impairment, and increased fat mass. Eligible male patients will be randomly assigned to receive either creatine monohydrate or a placebo (maltodextrin) in a doub

Trial Details

NCT ID
NCT07463092
Phase
NA
Sponsor
University of Sao Paulo
Status
RECRUITING
Cancer Type
Prostate Cancer
Interventions
  • Creatine Monohydrate
  • Maltodextrin
  • Resistance training
Locations (sample)
  • São Paulo, São Paulo, Brazil|-23.5475,-46.63611

Key Eligibility Criteria

  • Men aged ≥ 40 years;
  • Patients with histologically or cytologically confirmed localized prostate cancer;
  • Patients who have undergone surgical castration or pharmacological castration with gonadotropin-releasing hormone (GnRH/LHRH) agonists or antagonis…
  • Patients receiving continuous or intermittent androgen deprivation therapy;

For full eligibility, visit ClinicalTrials.gov.

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