Utero-ovarian Transposition in Patients With Pelvic Malignancies Undergoing Whole Pelvic Radiotherapy

This study is designed as a Phase I clinical trial enrolling female patients aged 18-40 years who have been diagnosed with pelvic malignancies requiring whole pelvic external radiation therapy (WPXRT) and who express interest in preserving fertility and ovarian function. The trial's primary objective is to assess the feasibility and safety of uterine and ovarian transposition (UOT). Premenopausal women under the age of 40 will undergo UOT using a novel minimally invasive approach. Feasibility and safety will be evaluated through standardized postoperative assessments, including: (A) success

Trial Details

NCT ID

NCT07419490

Phase

NA

Sponsor

University of South Florida

Status

RECRUITING

Cancer Type

Colorectal Cancer

Interventions

• Uteroovarian transposition

Locations (sample)

• Tampa, Florida, United States|27.94752,-82.45843

Key Eligibility Criteria

• Age: Women 18 - 40 years of age who wish to preserve their fertility.
• Malignancy: Diagnosis of pelvic malignancies that require radiotherapy, including:
• Colon and rectal cancer with tumors.
• Anal cancer.

For full eligibility, visit ClinicalTrials.gov.

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