Safety and Efficacy Study of BAFF-R CAR-T Cells in Adult Subjects With CD19-Negative Relapsed or Refractory B-Cell Lymphoma

The purpose of this study is to evaluate the safety and tolerability of BAFF-R CAR-T Cells in Adult Subjects with CD19-Negative relapsed or refractory B-Cell Lymphoma.

Trial Details

NCT ID
NCT07369492
Phase
PHASE1
Sponsor
Jiangsu Topcel-KH Pharmaceutical Co., Ltd.
Status
RECRUITING
Cancer Type
Lymphoma
Interventions
  • BAFF-R CAR-T cells
Locations (sample)
  • Suzhou, China|31.30408,120.59538

Key Eligibility Criteria

  • 1\. Subjects voluntarily participate in clinical research and sign informed consent.
  • 2\. Subjects with CD19-negative relapsed or refractory B-cell lymphoma: a) failure to achieve CR after 6 cycles, or PR after 3 cycles, of first-lin…
  • 3\. Expected survival ≥ 3 months.
  • 4\. BAFF-R expression are detected on tumor cells of subjects by flow cytometry or immunohistochemistry.

For full eligibility, visit ClinicalTrials.gov.

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