Sonoporation and Tumor Microenvironment Response in Colorectal Liver Metastases

This study is an investigator-initiated, randomized controlled trial enrolling patients with colorectal liver metastases. The objectives are to evaluate the safety and efficacy of contrast-enhanced ultrasound (CEUS)-mediated sonoporation as a potential therapeutic intervention and to investigate whether sonoporation can modulate the tumor microenvironment toward a more immune-active state

Trial Details

NCT ID
NCT07365527
Phase
NA
Sponsor
Zealand University Hospital
Status
RECRUITING
Cancer Type
Colon Cancer Colorectal Cancer
Interventions
  • Low-intensity contrast enhanced ultrasound
  • High-intensity contrast enhanced ultrasound
Locations (sample)
  • Copenhagen, Denmark|55.67594,12.56553
  • Køge, Denmark|55.45802,12.18214

Key Eligibility Criteria

  • Adult patients (≥18 years)
  • Ability to provide written informed consent
  • Histopathological confirmed colorectal adenocarcinoma
  • Scheduled for liver resection or ablation at the Rigshospital, or admitted to oncologic treatment due to colorectal liver metastases (CLM) at Zeala…

For full eligibility, visit ClinicalTrials.gov.

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