Strategic Endocrine Therapy and Targeted Radiotherapy for Prostate Cancer

The goal of this clinical trial is to study definitive external beam radiation therapy together with drugs called androgen deprivation therapy (ADT) in patients with prostate cancer. The investigators want to find out if these drugs work the same way if they are given for 6 months or for the usual 18 months in patients who receive also definitive external beam radiotherapy. The investigators will also learn about the safety of the treatments. The main questions the study aims to answer are: Do patients who get radiation therapy plus 6 months of androgen deprivation therapy need other hormone

Trial Details

NCT ID
NCT07364071
Phase
PHASE2
Sponsor
University of California, San Diego
Status
RECRUITING
Cancer Type
Prostate Cancer
Interventions
  • Radiation therapy
Locations (sample)
  • La Jolla, California, United States|32.84727,-117.2742

Key Eligibility Criteria

  • Histologically confirmed adenocarcinoma of the prostate.
  • High-risk localized prostate cancer, defined as ≥1 of the following (per National Comprehensive Cancer Network or D'Amico criteria):
  • Prostate specific antigen ≥ 20 ng/mL
  • Gleason score 8-10

For full eligibility, visit ClinicalTrials.gov.

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