Vascular Optimized Radiotherapy Tuned to Critical Structures for Erectile Function Using High-Precision X-Ray Treatment

With people living longer after being treated for prostate cancer, quality of life has become a concern when considering the treatment plan. Sometimes after radiation therapy, patients may experience problems that affect the urinary and bowel systems, along with sexual function. Stereotactic body radiotherapy (SBRT) is a type of radiation technique that delivers five high doses of radiation. At University of California at Los Angeles (UCLA), we have the option to administer SBRT in both our CT-guided and MRI-guided radiation machines. This trial aims to determine the most effective method fo

Trial Details

NCT ID
NCT07293585
Phase
PHASE3
Sponsor
Jonsson Comprehensive Cancer Center
Status
RECRUITING
Cancer Type
Prostate Cancer
Interventions
  • Neurovascular sparing stereotactic body radiation therapy
Locations (sample)
  • Los Angeles, California, United States|34.05223,-118.24368

Key Eligibility Criteria

  • Histologically confirmed, clinically localized adenocarcinoma of the prostate.
  • Staging workup as recommended by the National Comprehensive Cancer Network (NCCN) on the basis of risk grouping.
  • a. Advanced imaging studies (i.e. prostate-specific membrane antigen \[PSMA\] positron emission tomography \[PET\]/CT and fluciclovine PET/CT scan)…
  • No evidence of metastatic disease in lymph nodes above the bifurcation of the renal arteries, or in bones or visceral organs (nodal disease identif…

For full eligibility, visit ClinicalTrials.gov.

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