A Study to Evaluate the Safety and Tolerability of Pumitamig Alone or In Combination With Ipilimumab in Participants With First-Line Advanced or Unresectable Hepatocellular Carcinoma (HCC) (ROSETTA HCC-206)

The purpose of this study is to evaluate the safety and tolerability of Pumitamig alone or in combination with Ipilimumab in participants with first-line advanced or unresectable Hepatocellular Carcinoma (HCC)

Trial Details

NCT ID
NCT07291076
Phase
PHASE1 / PHASE2
Sponsor
Bristol-Myers Squibb
Status
RECRUITING
Cancer Type
Hepatocellular Carcinoma (HCC) Liver Cancer
Interventions
  • Pumitamig
  • Ipilimumab
  • Atezolizumab
  • Bevacizumab
Locations (sample)
  • Los Angeles, California, United States|34.05223,-118.24368
  • Chicago, Illinois, United States|41.85003,-87.65005
  • Hackensack, New Jersey, United States|40.88593,-74.04347
  • Mineola, New York, United States|40.74927,-73.64068
  • Portland, Oregon, United States|45.52345,-122.67621

Key Eligibility Criteria

  • Participants must have a histologically confirmed diagnosis of locally advanced or unresectable Hepatocellular Carcinoma (HCC).
  • Participants must have an Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1.
  • Participants must have no prior systemic therapy for advanced/ unresectable HCC.
  • Participants must have measurable disease as per Response Evaluation Criteria in Solid Tumors (RECIST) v1.1.

For full eligibility, visit ClinicalTrials.gov.

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