A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

The purpose of this study is to evaluate the efficacy and safety of standard-of-care chemotherapy and bevacizumab with or without INCA33890 in the first-line treatment of metastatic microsatellite stable colorectal cancer.

Trial Details

NCT ID
NCT07284849
Phase
PHASE3
Sponsor
Incyte Corporation
Status
RECRUITING
Cancer Type
Colon Cancer Colorectal Cancer
Interventions
  • INCA33890
  • Placebo
  • Bevacizumab
  • FOLFOX
Locations (sample)
  • Mobile, Alabama, United States|30.69436,-88.04305
  • Tucson, Arizona, United States|32.22174,-110.92648
  • Tucson, Arizona, United States|32.22174,-110.92648
  • Fountain Valley, California, United States|33.70918,-117.95367
  • Fullerton, California, United States|33.87029,-117.92534

Key Eligibility Criteria

  • Stage IV colorectal adenocarcinoma not amenable to curative resection.
  • No prior systemic treatment for unresectable or metastatic disease. Participants who received adjuvant or neoadjuvant therapy may enroll if there w…
  • Measurable disease per RECIST v1.1.
  • ECOG performance status of 0 or 1.

For full eligibility, visit ClinicalTrials.gov.

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