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NCT07253896
Efficacy and Safety of AK104 Combined With Chemotherapy and Cetuximab or Bevacizumab
Evaluate the objective response rate (ORR) of AK104 combined with chemotherapy and cetuximab or bevacizumab in second-line treatment of MSS type advanced colorectal cancer
Trial Details
NCT ID NCT07253896
Phase PHASE2
Sponsor Second Affiliated Hospital, School of Medicine, Zhejiang University
Status RECRUITING
Cancer Type Colon Cancer Colorectal Cancer
Interventions AK104 and cetuximab or bevacizumab and FOLFIRI
Locations (sample) Hangzhou, Zhejiang, China|30.29365,120.16142 Hangzhou, China|30.29365,120.16142
Key Eligibility Criteria
1\. Voluntarily sign a written ICF. 2. Age at enrollment: ≥ 18 years old, ≤ 75 years old, both male and female. 3. The Eastern Cancer Collaborative… 4\. The expected survival period is ≥ 3 months. 5. Metastatic colorectal adenocarcinoma confirmed by histology or cytology. 6. Microsatellite insta… 8\. Previously only received first-line systemic anti-tumor therapy based on oxaliplatin (FOLFOX or CAPOX), and other systemic anti-tumor treatment… According to RECIST v1.1, subjects must have at least one measurable lesion. For subjects who have previously received radiotherapy, if there are n…
For full eligibility, visit ClinicalTrials.gov .