Conformal Ablative Radiotherapy in Older Women (CARMEN) With Breast Cancer Undergoing Non-Operative Management

This phase II study evaluates SABR as non-operative treatment for women aged 65+ with ER-positive, HER2-negative breast cancer ≤5 cm and no lymph node involvement. Eligible patients, including those previously on endocrine therapy, receive 5 SABR treatments, followed by monitoring of quality of life and assessment of treatment-related toxicity.

Trial Details

NCT ID
NCT07242118
Phase
NA
Sponsor
University of Kansas Medical Center
Status
RECRUITING
Cancer Type
HER2 Positive Breast Cancer
Interventions
  • SABR
Locations (sample)
  • Kansas City, Kansas, United States|39.11417,-94.62746
  • Kansas City, Kansas, United States|39.11417,-94.62746

Key Eligibility Criteria

  • Willing and able to provide written informed consent obtained to participate in the study and HIPAA authorization for release of personal health in…
  • Women greater than or equal to age 65 years
  • Diagnosis of invasive carcinoma of breast undergoing non-operative management
  • Previously untreated OR previously treated with primary ET or chemotherapy, with either stable or progressive localized disease.

For full eligibility, visit ClinicalTrials.gov.

Check If You May Be Eligible

Trialify translates complex eligibility criteria into plain yes-or-no questions to help you understand if this trial might be right for you.

Find HER2 Positive Breast Cancer Trials on Trialify →