A Double-blind Non Inferiority Clinical Trial to Compare the Nephroprotection of Cilastatn Versus Thiosulfate in Patients Undergoing Debulking Surgery With Intraoperative Hyperthermic Intraperitoneal Chemotherapy With Cisplatin.

Trial Details

NCT ID

NCT07229040

Phase

PHASE2

Sponsor

Hospital General Universitario Gregorio Marañon

Status

RECRUITING

Cancer Type

Ovarian Cancer

Interventions

• cilastatine
• tiosulfate

Locations (sample)

• Madrid, Madrid, Spain|40.4165,-3.70256

Key Eligibility Criteria

• Age: adult patients aged 18-75 years.
• Sex: female. Eastern Cooperative Oncology Group Performance Status (ECOG PS) ≤ 2. General condition: patients eligible for major surgery, with crea…
• Patients evaluated by the Anesthesiology Department and deemed fit for surgery. Signed informed consent. Disease confined to the abdomen: CRS + HIP…
• Multidisciplinary Committee evaluation: radiological PCI is assessed, and the likelihood of achieving complete cytoreduction is estimated to determ…

For full eligibility, visit ClinicalTrials.gov.

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