Tongue-out Radiation Therapy (TORT) for the Mitigation of Radiotherapy-related Toxicities in Patients With Head and Neck Cancer

Our institution recently began incorporating a novel "tongue-out" radiation therapy (TORT) technique for patients with head and neck tumors at particular subsites (oropharynx, larynx, hypopharynx). Protruding the tongue, i.e. "tongue-out" position, induces anatomical changes that facilitate decreased radiation dose to the oral tongue and PCM. The long-term goal is to determine whether TORT results in reduced severity and faster recovery from acute treatment-related toxicities (particularly mucositis, dysphagia, and dysgeusia) and improved long-term swallowing function and taste compared to tra

Trial Details

NCT ID
NCT07227792
Phase
NA
Sponsor
Yvonne Mowery
Status
RECRUITING
Cancer Type
Head and Neck Cancer
Interventions
  • Tongue-out radiation therapy (TORT)
Locations (sample)
  • Pittsburgh, Pennsylvania, United States|40.44062,-79.99589

Key Eligibility Criteria

  • Must have histologically or cytologically confirmed squamous cell carcinoma of the oropharynx, larynx, or hypopharynx (cT0-4, N0-3, M0-1).
  • Patients with metastatic disease will be included if the following criteria are met:
  • Definitive RT dose is planned for the primary site
  • The number of metastatic lesions is ≤5

For full eligibility, visit ClinicalTrials.gov.

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