A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies

The purpose of this study is to evaluate the safety, tolerability, and efficacy of BMS-986523 alone and in combination with anti-cancer agents in participants with advanced solid malignancies

Trial Details

NCT ID
NCT07223047
Phase
PHASE1 / PHASE2
Sponsor
Bristol-Myers Squibb
Status
RECRUITING
Cancer Type
Non-Small Cell (NSCLC) Lung Cancer
Interventions
  • BMS-986523
  • Gemcitabine
  • Nab-Paclitaxel
  • Cetuximab
  • Pembrolizumab
Locations (sample)
  • Baltimore, Maryland, United States|39.29038,-76.61219
  • San Antonio, Texas, United States|29.42412,-98.49363
  • West Valley City, Utah, United States|40.69161,-112.00105
  • Fairfax, Virginia, United States|38.84622,-77.30637
  • Vancouver, British Columbia, Canada|49.24966,-123.11934

Key Eligibility Criteria

  • Participants must have a histologically confirmed diagnosis of a locally advanced and unresectable or metastatic solid tumor malignancy with a know…
  • Participants must, for Arm D, have a PD-L1 expression (≥50%).
  • Participants must have previously received, be ineligible for, or decline (after having been provided adequate information to make an informed deci…

For full eligibility, visit ClinicalTrials.gov.

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