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NCT07222267
An Investigational Study of BG-75202 Alone and in Combination With Other Therapeutic Agents in Adults With Advanced Solid Tumors
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics, and preliminary antitumor activity of BG-75202 (KAT6A/B inhibitor) alone and in combination with other therapies in participants with breast cancer and other advanced solid tumors.
Trial Details
NCT ID NCT07222267
Phase PHASE1
Sponsor BeOne Medicines
Status RECRUITING
Cancer Type Breast Cancer
Interventions BG-75202 CDK4 Inhibitor Estrogen Receptor Antagonist Aromatase Inhibitor
Locations (sample) Birmingham, Alabama, United States|33.52066,-86.80249 New Haven, Connecticut, United States|41.30815,-72.92816 St Louis, Missouri, United States|38.62727,-90.19789 Austin, Texas, United States|30.26715,-97.74306 Houston, Texas, United States|29.76328,-95.36327
Key Eligibility Criteria
Part 1A: Participants with histologically or cytologically confirmed advanced, metastatic breast cancer and other solid tumors who have exhausted, … Part 1B and Part 2A: Participants with advanced breast cancer with 1 to 3 prior lines of systemic therapy in the metastatic setting. Prior lines in… Parts 2B and 2C: Participants with advanced breast cancer enrolled in regions where cyclin-dependent kinase 4/6 (CDK4/6) inhibitors are not approve… Participants with breast cancer must have histologically or cytologically confirmed advanced breast cancer at the time of most recent testing, base…
For full eligibility, visit ClinicalTrials.gov .
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