Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

The purpose of this study is to evaluate INCB123667 versus investigator's choice of chemotherapy in participants with platinum-resistant ovarian cancer with cyclin E1 overexpression.

Trial Details

NCT ID
NCT07214779
Phase
PHASE3
Sponsor
Incyte Corporation
Status
RECRUITING
Cancer Type
Ovarian Cancer
Interventions
  • INCB123667
  • Investigator's choice of chemotherapy
Locations (sample)
  • Anchorage, Alaska, United States|61.21806,-149.90028
  • Tucson, Arizona, United States|32.22174,-110.92648
  • Duarte, California, United States|34.13945,-117.97729
  • Los Angeles, California, United States|34.05223,-118.24368
  • Aurora, Colorado, United States|39.72943,-104.83192

Key Eligibility Criteria

  • Histological diagnosis of high-grade serous epithelial ovarian, fallopian tube, or primary peritoneal cancer.
  • Have platinum-resistant disease.
  • Participants who have only had 1 line of platinum-based therapy must have received at least 4 cycles of platinum containing regimen.
  • Participants who have received 2 to 4 lines of platinum-based therapy must have progressed on or within 6 months after the last dose of platinum.

For full eligibility, visit ClinicalTrials.gov.

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