Combined Gamma Knife/Linac Radiosurgery for Large Brain Tumors / Metastases

When cancer spreads to the brain, doctors often use a precise type of radiation therapy called stereotactic radiosurgery (SRS) to treat these tumors. This treatment can effectively control brain tumors while helping protect healthy brain tissue. However, when brain tumors or the areas where tumors were surgically removed are larger, treatment outcomes in terms of side effects and tumour control can become worse. Specifically, standard SRS on larger areas can have lower tumour control and higher risk of side effects, particularly a condition called radiation necrosis, which can cause swelling a

Trial Details

NCT ID
NCT07162246
Phase
PHASE2
Sponsor
Sunnybrook Health Sciences Centre
Status
RECRUITING
Cancer Type
Brain Cancer
Interventions
  • Radiation Therapy
Locations (sample)
  • Toronto, Ontario, Canada|43.70643,-79.39864

Key Eligibility Criteria

  • Presence of up to two large intracranial lesions
  • Up to 10 (previously untreated, or progressing after previous treatment) brain metastases at the time of enrollment on the diagnostic MRI (which in…
  • Age =\> 18 years
  • Eastern Cooperative Oncology Group (ECOG) performance status of 0-2

For full eligibility, visit ClinicalTrials.gov.

Check If You May Be Eligible

Trialify translates complex eligibility criteria into plain yes-or-no questions to help you understand if this trial might be right for you.

Find Brain Cancer Trials on Trialify →