Efficacy of Perioperative Opioid Sparing Techniques on Time to Initiation of Chemotherapy

The primary purpose of this study is to determine if intrathecal morphine (ITM) administration is superior to quadratus lumborum block or surgeon administered transversus abdominis plane (TAP) blocks result in decreased time to initiation of chemotherapy following oncologic surgery. The secondary objectives of this study are to determine: * The difference between interventions in time to return of bowel function in days * The difference between interventions in incidence of opioid related adverse drug events (ORADEs) * The difference between interventions in cumulative and post-operative tot

Trial Details

NCT ID
NCT07153614
Phase
NA
Sponsor
University of Tennessee Graduate School of Medicine
Status
RECRUITING
Cancer Type
Colon Cancer Colorectal Cancer
Interventions
  • Intrathecal Morphine Block
  • Bilateral Quadratus Lumborum Block
  • Bilateral Transverse Abdominis Plane Block
Locations (sample)
  • Knoxville, Tennessee, United States|35.96064,-83.92074

Key Eligibility Criteria

  • 18-80 years of age
  • Patients undergoing open surgery for foregut, HPB, and colorectal cancer
  • Able to read and understand study procedures
  • Willing to participate and sign an ICF

For full eligibility, visit ClinicalTrials.gov.

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