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NCT07150208
T-DXd With or Without Bevacizumab for HER2-low Breast Cancer With Brain Metastasis
A phase II, open-label, multicenter, randomized controlled trial exploring the efficacy and safety of Trastuzumab Deruxtecan combined with or without Bevicizumab in HER2-low breast cancer with brain metastasis.
Trial Details
NCT ID NCT07150208
Phase PHASE2
Sponsor Fudan University
Status RECRUITING
Cancer Type Breast Cancer
Interventions Bevacizumab (Bev) Trastuzumab Deruxtecan (T-DXd)
Locations (sample) Shanghai, China|31.22222,121.45806
Key Eligibility Criteria
ECOG score of 0 to 1. Expected survival period greater than 12 weeks. Histologically confirmed invasive HER2-low expressing breast cancer (specific definition: breast cancer patients with low expression of human epide… Tumor stage: recurrent or metastatic breast cancer; local recurrence must be confirmed by the researcher to be unable to undergo radical surgical r…
For full eligibility, visit ClinicalTrials.gov .
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