Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of WEF-001 as Monotherapy in Advanced KRAS-Mutant Solid Tumours.

This is a study designed to assess the safety, tolerability, pharmacokinetics and preliminary efficacy of WEF-001 as monotherapy in patients with Advanced KRAS-mutant solid tumours.

Trial Details

NCT ID
NCT07148128
Phase
PHASE1 / PHASE2
Sponsor
Auricula Biosciences Inc.
Status
RECRUITING
Cancer Type
Non-Small Cell (NSCLC) Lung Cancer
Interventions
  • WEF-001
Locations (sample)
  • Dallas, Texas, United States|32.78306,-96.80667
  • San Antonio, Texas, United States|29.42412,-98.49363
  • Toronto, Ontario, Canada|43.70643,-79.39864
  • Headington, Oxford, United Kingdom|51.75737,-1.21974

Key Eligibility Criteria

  • Advanced KRAS-mutant solid tumor: pancreatic ductal adenocarcinoma, colorectal cancer, non small cell lung cancer, platinum-resistant serous ovaria…
  • Progressive disease following at least one line of standard of care therapy
  • Measurable disease as defined by RECIST v1.1

For full eligibility, visit ClinicalTrials.gov.

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