HEARTS Trial for Thoracic Cancers

The goal of this clinical trial is to compare a new way of using magnetic resonance-guided adaptive radiation therapy (MRgART) to the standard of care linear accelerator (LINAC) radiation treatment in people with cancer in the thoracic region near the heart. The main question it aims to answer is whether MRgART affects the heart differently than LINAC. Participants will: * Receive radiation therapy * Undergo MRIs and bloodwork * Complete quality of life questionnaires

Trial Details

NCT ID
NCT07132918
Phase
PHASE2
Sponsor
University of Wisconsin, Madison
Status
RECRUITING
Cancer Type
Lung Cancer
Interventions
  • MRgART
  • LINAC
Locations (sample)
  • Madison, Wisconsin, United States|43.07305,-89.40123

Key Eligibility Criteria

  • Age \> 18 years at the time of consent.
  • Dosimetric eligibility criteria met using endpoints from QUANTEC (\>10% of heart receives \> 25 Gy) as determined through rapid auto-planning
  • Participants with histologically or cytologically proven AJCC, 8th edition including:
  • Stage IIB, IIIA, IIIB, IIIC, or IV non-operable non-small cell lung cancer

For full eligibility, visit ClinicalTrials.gov.

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