Combination of Concurrent Chemoradiotherapy With Surufatinib and Tislelizumab in Patients With Locally Advanced Non-Small Cell Lung Cancer

This is a prospective, single-arm, phase II clinical study designed to evaluate the efficacy and safety of surufatinib and tislelizumab in combination with concurrent chemoradiotherapy, followed by consolidation therapy with tislelizumab plus surufatinib, in patients with unresectable, locally advanced stage III non-small cell lung cancer (NSCLC).

Trial Details

NCT ID
NCT07086456
Phase
PHASE2
Sponsor
Sun Yat-sen University
Status
RECRUITING
Cancer Type
Lung Cancer
Interventions
  • Surufatinib
  • Tislelizumab
  • Concurrent Chemotherapy
  • Radiotherapy
Locations (sample)
  • Guangzhou, Guangdong, China|23.11667,113.25

Key Eligibility Criteria

  • A written and dated informed consent form must be obtained prior to the initiation of any study-specific procedures.
  • Male or female patients aged 18 to 75 years.
  • Histologically or cytologically confirmed locally advanced, unresectable non-small cell lung cancer (NSCLC) (Stage IIIA-IIIC).
  • Tumor sample requirement: Adequate archival, unstained tumor tissue samples must be provided for analysis.

For full eligibility, visit ClinicalTrials.gov.

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