Comparing the Effectiveness of Less Invasive Procedures With the Current Standard of Care for the Treatment of Older Adults With Early-Stage Melanoma

This phase III trial compares the effect of wide local excision (WLE) alone to usual care with WLE plus sentinel lymph node (SLN) biopsy for the treatment of older adults with early-stage melanoma. A WLE is a surgical procedure performed to cut out an abnormal lesion and some surrounding normal tissue. This is sometimes followed by a SLN biopsy, in which lymph nodes that tumor cells could spread to are removed as well. Using WLE alone may be just as effective as usual care in treating older adults with early-stage melanoma.

Trial Details

NCT ID
NCT07068074
Phase
PHASE3
Sponsor
ECOG-ACRIN Cancer Research Group
Status
RECRUITING
Cancer Type
Melanoma
Interventions
  • Adjuvant Therapy
  • Comprehensive Geriatric Assessment
  • Computed Tomography
  • Positron Emission Tomography
  • Questionnaire Administration
  • Sentinel Lymph Node Biopsy
Locations (sample)
  • Birmingham, Alabama, United States|33.52066,-86.80249
  • Daphne, Alabama, United States|30.60353,-87.9036
  • Fairhope, Alabama, United States|30.52297,-87.90333
  • Mobile, Alabama, United States|30.69436,-88.04305
  • Saraland, Alabama, United States|30.82074,-88.07056

Key Eligibility Criteria

  • Patient must be ≥ 75 years of age.
  • Patient must have Eastern Cooperative Oncology Group (ECOG) performance status of 0-2.
  • Patient must have the ability to understand and the willingness to sign a written informed consent document. Patients with impaired decision-making…
  • Patient must have newly diagnosed primary cutaneous melanoma with wide local excision (WLE) and sentinel lymph node (SLN) biopsy indicated per the …

For full eligibility, visit ClinicalTrials.gov.

Check If You May Be Eligible

Trialify translates complex eligibility criteria into plain yes-or-no questions to help you understand if this trial might be right for you.

Find Melanoma Trials on Trialify →