Durvalumab as Consolidation for Patients LS-SCLC

Small-Cell Lung Cancer (SCLC) accounts for 10% to 15% of new lung cancers and is a highly aggressive neuroendocrine tumor. In the past 30 years, the treatment of SCLC has made very limited progress, and basically made breakthroughs in radiotherapy and chemotherapy. With the advent of the immune era, immunotherapy has achieved initial results in the treatment of SCLC. Approximately one-third of patients with small cell lung cancer are in limited-stage (LS-SCLC) disease at first diagnosis. Except for a very small number of patients with T1-2N0 who can be treated with surgery or stereotactic radi

Trial Details

NCT ID
NCT07055581
Phase
PHASE2
Sponsor
Qian Chu
Status
RECRUITING
Cancer Type
Lung Cancer
Interventions
  • Induction Durvalumab +etoposide/platinum +Radiochemotherapy+ durvalumab maintenance
Locations (sample)
  • Zhengzhou, Henan, China|34.75778,113.64861
  • Wuhan, Hubei, China|30.58333,114.26667

Key Eligibility Criteria

  • Capable of giving signed informed consent which includes compliance with the requirements and restrictions listed in the informed consent form (ICF…
  • Histologically or cytologically confirmed small cell lung cancer
  • Limited-stage, defined as stage I-III SCLC (T any, N any, M0). Patients who are Stage I or II must be medically inoperable as determined by investi…
  • Age \> 18 years.

For full eligibility, visit ClinicalTrials.gov.

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