Intermittent Versus Continuous Venetoclax With Acalabrutinib for CLL/SLL

This is a randomized Phase II study of intermittent versus continuous venetoclax therapy with Acalabrutinib in previously untreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)

Trial Details

NCT ID
NCT07014917
Phase
PHASE2
Sponsor
Zulfa Omer
Status
RECRUITING
Cancer Type
Lymphoma
Interventions
  • Venetoclax
  • Acalabrutinib
Locations (sample)
  • Cincinnati, Ohio, United States|39.12711,-84.51439

Key Eligibility Criteria

  • Diagnosis of Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL) as defined by the IWCLL including variation of flow cytometry, …
  • a. Note: Variation in flow cytometry is defined as patients who have atypical immunophenotyping for CLL (CD5 negative, CD23 negative or surface exp…
  • Men and Women ≥18 years of age.
  • Eastern Cooperative Oncology Group (ECOG) performance status of 0, 1, or 2 with no deterioration over the previous 2 weeks prior to baseline or day…

For full eligibility, visit ClinicalTrials.gov.

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