Pyrotinib Combined With Dalpiciclib Combined With Letrozole in ER-positive and HER2-positive Advanced Breast Cancer

This is a a multicenter Phase II clinical study investigating efficacy of pyrotinib combined with dalpiciclib combined with letrozole in ER-positive and HER2-positive advanced breast cancer patients. The sample size is 63.

Trial Details

NCT ID
NCT07014410
Phase
PHASE2
Sponsor
Zhejiang Cancer Hospital
Status
RECRUITING
Cancer Type
HER2 Positive Breast Cancer
Interventions
  • pyrotinib dalpiciclib letrozole
Locations (sample)
  • Hangzhou, Zhejiang, China|30.29365,120.16142

Key Eligibility Criteria

  • The subjects voluntarily joined the study, signed the informed consent, and had good compliance
  • Postmenopausal or premenopausal/perimenopausal women aged ≥18 years and ≤75 years
  • Patients with recurrent/metastatic breast cancer confirmed by histopathology with positive ER expression and positive HER2 expression
  • Have at least one extracranial measurable lesion that meets RECIST 1.1 criteria

For full eligibility, visit ClinicalTrials.gov.

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