Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity

This study is being done to answer the following questions: Can we lower the chance of your gastric cancer from growing or spreading by administering paclitaxel chemotherapy directly into your abdominal cavity in addition to chemotherapy given through a vein in your arm? Will administering paclitaxel chemotherapy directly into your abdominal cavity, in addition to chemotherapy given through a vein in your arm help you live longer? We are doing this study because we want to find out if this approach is better or worse than the usual approach for your gastric cancer. The usual approach is defin

Trial Details

NCT ID
NCT07001748
Phase
PHASE2 / PHASE3
Sponsor
ECOG-ACRIN Cancer Research Group
Status
RECRUITING
Cancer Type
Gastric Cancer
Interventions
  • Standard of Care Chemotherapy
  • Biospecimen Collection
  • Computed Tomography
  • Diagnostic Laparoscopy
  • Intraperitoneal Port Placement
  • Magnetic Resonance Imaging
Locations (sample)
  • Irvine, California, United States|33.66946,-117.82311
  • Los Angeles, California, United States|34.05223,-118.24368
  • Orange, California, United States|33.78779,-117.85311
  • Palo Alto, California, United States|37.44188,-122.14302
  • Aurora, Colorado, United States|39.72943,-104.83192

Key Eligibility Criteria

  • STEP 0 REGISTRATION:
  • Patient must be at least 18 years of age
  • Patient must have an Eastern Cooperative Oncology Group (ECOG) performance status of 0-1
  • Patient must have histologically or cytologically confirmed microsatellite stable (MSS) or mismatch repair (MMR) protein expression proficient prim…

For full eligibility, visit ClinicalTrials.gov.

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