Image-guided, Tumor-focused Radiotherapy Treatment in Intermediate and High-risk Prostate Cancer

This is a phase II non-blinded randomized controlled trial of image-guided, tumor-focused radiotherapy in patients with intermediate- or high-risk prostate cancer planning to undergo definitive radiotherapy with or without systemic therapy. The image-guided, tumor-focused radiotherapy will be compared to standard, whole-prostate treatment. The investigators hypothesize that tumor-focused radiotherapy reduces the radiation dose to organs close to the prostate, possibly leading to decreased acute toxicity to the genitourinary and gastrointestinal organs. The investigators will measure acute and

Trial Details

NCT ID
NCT06990542
Phase
PHASE2
Sponsor
University of California, San Diego
Status
RECRUITING
Cancer Type
Prostate Cancer
Interventions
  • Image-guided tumor-focused radiation therapy
Locations (sample)
  • La Jolla, California, United States|32.84727,-117.2742

Key Eligibility Criteria

  • Provision of signed and dated informed consent form
  • Stated willingness to comply with all study procedures and availability for the duration of the study
  • At least 18 years old
  • Histologic confirmation of prostate adenocarcinoma with plan for curative-intent radiation therapy

For full eligibility, visit ClinicalTrials.gov.

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