ARMSTRONG - Air entRainMent vS sTandard tReatment in nOn-expandable luNG

This is a randomised controlled trial evaluating whether controlled air introduction into pleural space (air entrainment) during pleural effusion drainage reduces pain, improves patient satisfaction, and facilitates more effective drainage in patients with non-expandable lung (NEL). NEL lung is a common complication in patients with malignant or chronic pleural effusions, where the lung fails to fully re-expand after fluid removal due to pleural disease or fibrosis. In these patients, drainage often creates excessive negative pressure within the pleural cavity, leading to pain, vasovagal epis

Trial Details

NCT ID
NCT06959719
Phase
NA
Sponsor
Cambridge University Hospitals NHS Foundation Trust
Status
RECRUITING
Cancer Type
Lung Cancer
Interventions
  • Air Entrainment - intentional introduction of the atmospheric air into the pleural space.
Locations (sample)
  • Cambridge, Cambridgeshire, United Kingdom|52.2,0.11667

Key Eligibility Criteria

  • Adults aged 18 years or older with a suspected or confirmed diagnosis of NEL and persistent pleural effusion.
  • Patients who are scheduled for pleural effusion drainage as part of their standard care.
  • Ability to adequately understand verbal or written information in English and provide informed consent in English.

For full eligibility, visit ClinicalTrials.gov.

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