A Global, Integrated, Personalized, Stage-related, Multimodal Therapeutic Approach for Rectal Adenocarcinoma Based on Organ Sparing and Mininvasivity

A phase II, single-center, non-profit, interventional study on patients affected by rectal adenocarcinoma. Patients will be stratified into three groups based on pre-treatment clinical stage. The study investigates and may propose a comprehensive, stage-specific, multimodal approach to rectal adenocarcinoma, with a focus on organ preservation even in early stages (cT1-2N0). When organ-sparing strategies are not feasible, the approach prioritizes minimally invasive techniques (laparoscopic and robotic) to reduce the physical, psychological, and quality-of-life impact on patients.

Trial Details

NCT ID
NCT06952101
Phase
NA
Sponsor
Fondazione del Piemonte per l'Oncologia
Status
RECRUITING
Cancer Type
Colorectal Cancer
Interventions
  • Sparing Approach
  • experimental chemoradiotherapy
  • Standard Chemotherapy
Locations (sample)
  • Candiolo, Turin, Italy|44.95858,7.59812

Key Eligibility Criteria

  • Patients aged ≥18 yrs old
  • Patients able to sign the informed consent
  • Patients with High Risk pT1 rectal adenocarcinoma endoscopically excised
  • Patients with cT2-3aN0 rectal adenocarcinoma who has complete/major response to EXPERIMENTAL CRT

For full eligibility, visit ClinicalTrials.gov.

Check If You May Be Eligible

Trialify translates complex eligibility criteria into plain yes-or-no questions to help you understand if this trial might be right for you.

Find Colorectal Cancer Trials on Trialify →