Safety and Efficacy of Tremelimumab+Durvalumab(MEDI4736)+TACE in Unresectable Hepatocellular Carcinoma

Safety and Efficacy Evaluation of Tremelimumab Plus Durvalumab(MEDI4736) in Combination with Concurrent Transarterial Chemoembolization in Unresectable Hepatocellular carcinoma

Trial Details

NCT ID
NCT06911255
Phase
PHASE1 / PHASE2
Sponsor
Yoon Jun Kim
Status
RECRUITING
Cancer Type
Hepatocellular Carcinoma (HCC) Liver Cancer
Interventions
  • Tremelimumab Plus Durvalumab (MEDI4736)
  • Transarterial chemoembolization (TACE)
Locations (sample)
  • Seoul, South Korea|37.566,126.9784

Key Eligibility Criteria

  • 1\. Capable of giving signed informed consent which includes compliance with the requirements and restrictions listed in the informed consent form …
  • 2\. Male or female, aged ≥19 years at time of study entry. 3. Diagnosed with unequivocal HCC confirmed histologically or diagnosed radiologically a…
  • 4\. Barcelona clinic liver cancer (BCLC) staging intermediate (B) stage or BCLC advanced stage (C) HCC with or without minimal extrahepatic disease…
  • 5\. Must have at least 1 untreated measurable disease (untreated target lesion i.e. a viable lesion that has never been treated with locoregional t…

For full eligibility, visit ClinicalTrials.gov.

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