Testing a Functional Precision Medicine Approach to Select Chemotherapy for Metastatic Colorectal Cancer (COSENSE-1)

COSENSE-1 is an unblinded, phase II, single-armed, single center feasibility study for using a functional precision medicine platform to select oxaliplatin-based versus irinotecan-based chemotherapy regimens, for male and female participants aged 18 and older, with microsatellite stable (MSS)/proficient mismatch repair (pMMR) metastatic colorectal cancer (mCRC), that is incurable or not resectable with curative intent.

Trial Details

NCT ID
NCT06907342
Phase
PHASE2
Sponsor
St. Olavs Hospital
Status
RECRUITING
Cancer Type
Colon Cancer Colorectal Cancer
Interventions
  • FOLFOX or FOLFIRI
Locations (sample)
  • Trondheim, Norway|63.43049,10.39506

Key Eligibility Criteria

  • General conditions:
  • Age 18 or older
  • ECOG performance status 0 or 1
  • Obtained informed consent

For full eligibility, visit ClinicalTrials.gov.

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