Stroke Volume Variation Versus Central Venous Pressure Guidance for Reducing Perioperative Blood Loss During Open Liver Resection

Liver resection is a major surgery that can be associated with significant intraoperative blood loss and blood transfusion. Among high-volume centers, median intraoperative blood loss ranges between 300-800 ml. Excessive blood loss is a strong independent predictor of worsened postoperative outcomes, increasing morbidity and mortality rates by 20%-35%. Additionally, perioperative allogeneic blood transfusions are associated with deleterious outcomes, including tumor recurrence and increased rates of complications and death. The liver is a highly vascular organ with minimal vascular resistance

Trial Details

NCT ID

NCT06905015

Phase

NA

Sponsor

Warangkana Lapisatepun

Status

RECRUITING

Cancer Type

Liver Cancer

Interventions

• High stroke volume variation group

Locations (sample)

• Chiang Mai, Chiangmai, Thailand|18.79038,98.98468

Key Eligibility Criteria

• All genders, age 18 to 70 years old
• American Society of Anesthesiologists (ASA) physical status classification of I-III
• The patients who scheduled in elective open liver resection and diagnosed Hepatocellular Carcinoma, Cholangiocarcinoma, Liver metastasis, and Benig…

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