- IKF/AIO-QUINTIS - Evaluating Fruquintinib in Combination With Tislelizumab in Microsatellite Stable / Proficient Mismatch Repair (MSS/pMMR) Metastatic Colorectal Cancer Without Active Liver Metastases

This is a prospective, randomized, open-label, multicenter phase II investigating the therapy of Fruquintinib in combination with Tislelizumab in patients with MSS/pMMR metastatic colorectal cancer without liver metastases.

Trial Details

NCT ID
NCT06856837
Phase
PHASE2
Sponsor
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
Status
RECRUITING
Cancer Type
Colon Cancer Colorectal Cancer
Interventions
  • Fruquintinib
  • Tislelizumab
  • Trifluridine/tipiracil
  • Bevacizumab
Locations (sample)
  • Linz, Austria|48.30639,14.28611
  • Salzburg, Austria|47.79941,13.04399
  • Wiener Neustadt, Austria|47.80485,16.23196
  • Amberg, Germany|49.44287,11.86267
  • Bad Saarow, Germany|52.28333,14.06667

Key Eligibility Criteria

  • Patient\* provide signed informed consent form.
  • Patient is ≥ 18 years at the time of given informed consent.
  • Patient has been diagnosed with histologically or cytologically proven microsatellite stable (MSS)/proficient mismatch repair (pMMR) metastatic ade…
  • Known RAS (KRAS or NRAS) and BRAF V600E mutational status. Note: These mutations are mutually exclusive. Therefore, if one of the factors is mutate…

For full eligibility, visit ClinicalTrials.gov.

Check If You May Be Eligible

Trialify translates complex eligibility criteria into plain yes-or-no questions to help you understand if this trial might be right for you.

Find Colon Cancer Colorectal Cancer Trials on Trialify →