Thermoradiotherapy for Locally Advanced Head and Neck Cancer Patients

Patients with head and neck cancer treated with radiotherapy (RT) have a substantial change of recurrence of the tumor in the pharynx or lymph nodes in the neck. Once tumor and/or lymph nodes have recurred, the prognosis is poor. To increase the efficacy of RT, usually chemotherapy is added to the treatment. However, due to age or co-morbidity chemotherapy is not always feasible to give in all patients. In head and neck patients unfit for chemotherapy, there is a clinical need to increase the effectiveness of RT, without adding substantial toxicity. To this end, the use of thermotherapy in thi

Trial Details

NCT ID

NCT06761937

Phase

PHASE1

Sponsor

Erasmus Medical Center

Status

RECRUITING

Cancer Type

Head and Neck Cancer

Interventions

Thermotherapy
standard radiotherapy

Locations (sample)

Rotterdam, South Holland, Netherlands|51.9225,4.47917

Key Eligibility Criteria

Age \>= 18 years
Mouth opening before treatment of \>= 40 mm for women and \>= 45mm for men
Squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx, and larynx proven by cytology / histology.
Locally advanced disease (stage III-IV).

For full eligibility, visit ClinicalTrials.gov.

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