Testosterone Replacement Therapy for the Treatment of Low Testosterone in Hypogonadal Men With Localized Prostate Cancer on Active Surveillance

This phase IV trial studies the effects of testosterone replacement therapy (TRT) on treatment outcomes in hypogonadal men with prostate cancer that has not spread to other parts of the body (localized) and who are on active surveillance (AS). AS in prostate cancer involves closely watching the patient's condition through regular physical exams and blood tests, but not giving treatment unless there are changes in test results. It can be a practical alternative to treatment in localized prostate cancer. Hypogonadal men have low testosterone associated with symptoms such as low libido and erecti

Trial Details

NCT ID
NCT06733350
Phase
PHASE4
Sponsor
Roswell Park Cancer Institute
Status
RECRUITING
Cancer Type
Prostate Cancer
Interventions
  • Biopsy of Prostate
  • Biospecimen Collection
  • Magnetic Resonance Imaging
  • Patient Observation
  • Questionnaire Administration
  • Therapeutic Testosterone
Locations (sample)
  • Buffalo, New York, United States|42.88645,-78.87837

Key Eligibility Criteria

  • Men aged ≥ 18 years
  • Men with localized prostate cancer are eligible for active surveillance (National Comprehensive Cancer Network \[NCCN\] very low, low, and intermed…
  • Participant must understand the investigational nature of this study and sign an independent ethics committee/institutional review board approved w…

For full eligibility, visit ClinicalTrials.gov.

Check If You May Be Eligible

Trialify translates complex eligibility criteria into plain yes-or-no questions to help you understand if this trial might be right for you.

Find Prostate Cancer Trials on Trialify →