Surgery Alone Verus Sugery Combined with Dose-reduced Radiotherapy for Newly Diagnosed Stage I Nasopharyngeal Carcinoma

The goal of this clinical trial is to compare the efficacy and safety of endoscopic nasopharyngectomy combined with retropharyngeal lymph nodes dissection plus bilateral upper neck lymph node dissection or plus postoperative low-dose radiotherapy in newly diagnosed stage Ⅰ nasopharyngeal carcinoma.

Trial Details

NCT ID
NCT06688760
Phase
NA
Sponsor
Ming-Yuan Chen
Status
RECRUITING
Cancer Type
Head and Neck Cancer
Interventions
  • Endoscopic nasopharyngectomy combine Retropharyngeal lymphadenectomy and Low Dose Radiotherapy
  • Endoscopic nasopharyngectomy combine Retropharyngeal lymphadenectomy and Double upper neck lymph node dissection
Locations (sample)
  • Guangzhou, Guangdong, China|23.11667,113.25
  • Zhuhai, Guangdong, China|22.27694,113.56778

Key Eligibility Criteria

  • Inclusion Criteria:
  • Performance Status Score 0-1 points.
  • Non-keratinized carcinoma of the nasopharynx (differentiated or undifferentiated, i.e., WHO type II or III) confirmed histologically and/or cytolog…
  • According to the UICC/AJCC eighth edition staging, the patient is defined as T1N0M0 stage I.

For full eligibility, visit ClinicalTrials.gov.

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