Preoperative Partial Breast Irradiation in Early-Stage Breast Cancer

In the management of early breast cancer patients, postoperative radiotherapy following breast-conserving surgery has been established as the standard treatment. Over the past two decades, significant changes have occurred in radiotherapy for breast cancer, encompassing dose fractionation methods, radiotherapy techniques, and delineation of the radiation field. Hypofractionated radiotherapy has been reported in numerous randomized phase 3 studies to show equivalent tumor control rates, reduced acute side effects, and similar late side effects compared to conventional fractionation. Among hypof

Trial Details

NCT ID
NCT06677944
Phase
PHASE2
Sponsor
Yonsei University
Status
RECRUITING
Cancer Type
Lobular Carcinoma Breast Cancer
Interventions
  • Preoperative PBI
Locations (sample)
  • Seoul, South Korea|37.566,126.9784

Key Eligibility Criteria

  • Histologically confirmed ductal carcinoma in situ (DCIS) and invasive breast cancer.
  • cT1/cN0, tumor size ≤ 2.5cm
  • ECOG 0\~2 -ER+, HER2-

For full eligibility, visit ClinicalTrials.gov.

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