Clinical Study of SN301A Injection in the Treatment of Hepatocellular Carcinoma

This is a single-arm, open-label study of safety, tolerability, and anti-cancer activity of SN301A (an off-the-shelf CAR NK cell therapy) in patients with glypican-3 (GPC3)-positive advanced hepatocellular carcinoma.

Trial Details

NCT ID
NCT06652243
Phase
EARLY_PHASE1
Sponsor
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Status
RECRUITING
Cancer Type
Liver Cancer
Interventions
  • SN301A
Locations (sample)
  • Shanghai, Shanghai Municipality, China|31.22222,121.45806

Key Eligibility Criteria

  • Signed written informed consent (ICF) and capable of complying with protocol-specified visits and related procedures;
  • Age ≥ 18 years and ≤ 70 years, male or female;
  • According to the Guidelines for the Diagnosis and Treatment of Primary Liver Cancer of CSCO in 2024, hepatocellular carcinoma was Diagnosed and GPC…
  • Barcelona Clinic Liver Cancer (BCLC) stage determined to be unresectable Stage B or C hepatocellular carcinoma, including: disease progression foll…

For full eligibility, visit ClinicalTrials.gov.

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