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NCT06646627
Clinical Trial of Autologous B7-H3 CAR T Cells in Reoccurent Platinum-resistant Ovarian Tumors
This is a single site, open label, Phase 1 study using a 3 + 3 dose escalation design in two cohorts of adults with recurrent, platinum-resistant ovarian tumors.
Trial Details
NCT ID NCT06646627
Phase PHASE1
Sponsor Stanford University
Status RECRUITING
Cancer Type Ovarian Cancer
Interventions
Locations (sample) Palo Alto, California, United States|37.44188,-122.14302
Key Eligibility Criteria
Disease: Histologically or cytologically confirmed diagnosis of ovarian cancer including serous, endometrioid, clear cell, mucinous, mixed epitheli… Have measurable disease. Measurable disease is defined as at least 1 lesion that can be accurately measured in at least 1 dimension (longest diamet… B7-H3 positive expression on malignant cells is NOT required but archival tissue must be available, or the subject must be willing to undergo tissu… Age: ≥ 18 years of age
For full eligibility, visit ClinicalTrials.gov .
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