A Study to Compare the Efficacy and Safety of BMS-986489 (BMS-986012+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).

The Purpose of the Study is to Compare the Efficacy and Safety of BMS-986489 (Anti-fucosyl-GM1+ Nivolumab Fixed Dose Combination) in Combination with Carboplatin plus Etoposide to that of Atezolizumab with Carboplatin plus Etoposide as First-Line Therapy in Participants with Extensive-Stage Small Cell Lung Cancer.

Trial Details

NCT ID
NCT06646276
Phase
PHASE3
Sponsor
Bristol-Myers Squibb
Status
RECRUITING
Cancer Type
Small Cell (SCLC) Lung Cancer
Interventions
  • BMS-986489 (BMS-986012+Nivolumab)
  • Atezolizumab
  • Carboplatin
  • Etoposide
Locations (sample)
  • Daphne, Alabama, United States|30.60353,-87.9036
  • Hot Springs, Arkansas, United States|34.5037,-93.05518
  • Fort Myers, Florida, United States|26.62168,-81.84059
  • Orange City, Florida, United States|28.94888,-81.29867
  • St. Petersburg, Florida, United States|27.77086,-82.67927

Key Eligibility Criteria

  • Participants must have diagnosis of Extensive-Stage Small Cell Lung Cancer (ES-SCLC).
  • Participants must be Healthy enough to do their normal activities with little or no help based on the ECOG performance scale.
  • Participants must have at least one tumor that can be measured using special imaging techniques like a CT scan or MRI at a site other than the brai…

For full eligibility, visit ClinicalTrials.gov.

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