Evaluation of Irinotecan Liposome (II) Combined With 5-FU, LV, and Bevacizumab for mCRC

To observe and evaluate the efficacy and safety of irinotecan liposome (II) combined with 5-fluorouracil(5-FU), calcium leucovorin(LV), and bevacizumab in the treatment of metastatic colorectal cancer.

Trial Details

NCT ID
NCT06643793
Phase
PHASE2
Sponsor
Affiliated Hospital of Nantong University
Status
RECRUITING
Cancer Type
Colorectal Cancer
Interventions
  • Irinotecan liposome (ll) + 5-FU/LV + bevacizumab
Locations (sample)
  • Nanjing, Jiangsu, China|32.06167,118.77778

Key Eligibility Criteria

  • Age ≥ 18 years old and ≤ 75 years old, gender is not limited;
  • Diagnosis of colorectal cancer by histopathology and/or cytology, clinical Records showing inoperable advanced metastatic colon or rectal cancer (i…
  • At least 1 measurable target lesion according to RECIST v1.1 criteria (ie, non-nodal lesions with a CT scan length ≥10 mm and nodal lesions with a …
  • Prior first- or second-line oxaliplatin-based therapy with treatment failure or intolerance\*; Note: \*Treatment failure or intolerance is defined …

For full eligibility, visit ClinicalTrials.gov.

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